Amgen

AMGen (formerly Applied Molecular Genetics Inc.) is an American multinational biopharmaceutical company headquartered in Thousand Oaks, California bogner jas. Located in the Conejo Valley, AMGen is the world’s largest independent biotechnology firm. In 2013, the company’s largest selling product lines were Neulasta/Neupogen Maje Sale, two closely related drugs used to prevent infections in patients undergoing cancer chemotherapy; and Enbrel, a tumor necrosis factor blocker used in the treatment of rheumatoid arthritis and other autoimmune diseases. Other products include Epogen, Aranesp, Sensipar/Mimpara goedkope truien, Nplate, Vectibix, Prolia and XGEVA.

The word AMGen is a portmanteau of the company’s original name, Applied Molecular Genetics, which became the official name of the company in 1983 (three years after incorporation and coincident with its initial public offering). The company’s first chief executive officer, from 1980, was co-founder George B. Rathmann, followed by Gordon M. Binder in 1988, followed by Kevin W. Sharer in 2000. Robert A. Bradway became Amgen’s president and chief executive officer in May 2012 following Sharer’s retirement.
The company has made at least five major corporate acquisitions.
The following is an illustration of the company’s mergers, acquisitions, spin-offs and historical predecessors:
Amgen (Founded 1983 as Applied Molecular Genetics)
Synergen Inc (Acq 1994)
Kinetix Pharmaceuticals Inc (Acq 2000)
Immunex Corporation (Acq 2002)
Tularik Inc (Acq 2004)
Abgenix Inc (Acq 2006)
Avidia Inc (Acq 2006)
Alantos Pharmaceuticals (Acq 2007)
Ilypsa Inc (Acq 2007)
Alantos Pharmaceuticals Holdings Inc (Acq 2007)
BioVex Group Inc (Acq 2011)
Laboratório Químico Farmacêutico Bergamo Ltda (Acq 2011)
Micromet Inc (Acq 2012)
Mustafa Nevzat İlaç (Acq 2012)
KAI Pharmaceuticals (Acq 2012)
deCODE genetics (Acq 2012)
Onyx Pharmaceuticals (Acq 2013)
NextCODE genetics (Spun off 2013)
Dezima Pharma (Acq 2015)
As of December, 2013, Amgen had twelve approved drugs or therapeutic biologicals for seventeen conditions (conditions lists are highly generalized; see each article for more detail):
As of December 2013, Amgen had 11 drugs in Phase III clinical trials.
In November 2014 the company announced it was halting all trials of rilotumumab in advanced gastric cancer patients after one of the trials found more deaths in those who took the compound with chemotherapy miu miu handbags, than those without. Later in the same week, the company (in conjunction with AstraZeneca) reported positive results for brodalumab in a phase III trial comparing the compound with ustekinumab and a placebo in treating psoriasis.
In March 2015, the company announced it would license its Phase II candidate drug AMG 714 to developer Celimmune who plan to develop the anti-IL-15 monoclonal antibody for treatment against diet nonresponsive celiac disease and refractory celiac disease.

Mathieu Belie

a Compétitions nationales et continentales officielles uniquement. Dernière mise à jour le 22 juillet 2014.
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Mathieu Belie, né le 20 février 1988 à Toulouse soccer jerseys 2016 outlet, est un joueur de rugby à XV français qui évolue au poste de demi d’ouverture ou de demi de mêlée au sein de l’USA Perpignan (1,80 m pour 88 kg).

Ce jeune joueur est considéré au début des années 2010 comme l’un des joueurs de sa génération les plus prometteurs au poste de demi-d’ouverture. Pour Michel Marfaing, son ancien entraineur chez les espoirs du Stade toulousain, il est « le 10 de demain ». Mais le Stade toulousain ayant toujours fait de la polyvalence d’un joueur un de ses crédos, Bélie est aussi capable de jouer demi de mêlée, ailier ou arrière.
Il débute le rugby à Tournefeuille où il passe 7 années

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, passe ensuite par l’US Colomiers sandro femme. C’est à l’âge de 16 ans qu’il arrive au Stade toulousain où il débute avec les cadets A.
C’est lors de la saison 2007-2008 que ce polyvalent des lignes arrières (il peut jouer à la mêlée, à l’ouverture maillots de football, aux ailes et à l’arrière), 20 ans, effectue ses débuts dans le Top 14 à l’occasion de la rencontre Stade français – Stade toulousain. Cette saison-là, il dispute 3 matchs pour 154 minutes participant ainsi à la conquête du Bouclier de Brennus 2008 avec le Stade toulousain. Cette même saison, il est également sélectionné avec l’équipe de France des moins de 20 ans pour participer à la Coupe du Monde de Rugby aux Pays de Galles.
Lors de la saison 2008-2009, il est utilisé par Guy Novès en tant que troisième ouvreur derrière David Skrela et Frédéric Michalak. En 2009, avec une dizaine de matchs de championnat à son actif cette saison, il signe son premier contrat professionnel avec le Stade toulousain pour trois saisons.
Afin de gagner davantage de temps de jeu, il est prêté au MTGXV, puis rejoint le CA Brive lorsque le club de Montauban est rétrogradé administrativement en Fédérale 1. À la fin de la saison 2012, il quitte le CA Brive, relégué en Pro D2 et rejoint le Racing Métro 92 en 2012, l’Aviron Bayonnais en 2013 et l’USA Perpignan en 2014.
Dernière mise à jour le 02 juillet 2013
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Types of inhabited localities in Russia

The classification system of the types of inhabited localities in Russia, the former Soviet Union, and some other post-Soviet states has certain peculiarities compared to the classification systems in other countries.[citation needed]

During the Soviet time, each of the republics of the Soviet Union, including the Russian SFSR, had its own legislative documents dealing with classification of inhabited localities. After the dissolution of the Soviet Union, the task of developing and maintaining such classification in Russia was delegated to the federal subjects. While currently there are certain peculiarities to classifications used in many federal subjects, they are all still largely based on the system used in the RSFSR. In all federal subjects bags online, the inhabited localities are classified into two major categories: urban and rural red wing online.[citation needed] Further divisions of these categories vary slightly from one federal subject to another,[citation needed] but they all follow common trends described below.
In 1957, the procedures for categorizing urban-type settlements were further refined.
Multiple types of rural localities exist Free People Online Sale, some common through the whole territory of Russia

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, some specific to certain federal subjects. The most common types include:

Roger & Me

Roger & Me is a 1989 American documentary film directed by Michael Moore. Moore portrays the regional economic impact of General Motors CEO Roger Smith’s action of closing several auto plants in Flint, Michigan, reducing GM’s employees in that area from 80,000 in 1978 to about 50,000 in 1992. As of August 2015, GM employs approximately 7,200 workers in the Flint area, according to The Detroit News, and 5,000 workers according to MSNBC. In 2013 the film was selected for preservation in the United States National Film Registry by the Library of Congress as being “culturally, historically, or aesthetically significant”.

Moore begins by introducing himself and his family through 8 mm archival home movies; he describes himself as the Irish American Catholic middle-class son of a General Motors employee assembling AC spark plugs. Moore chronicles how GM had previously defined his childhood in Flint

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, Michigan, and how the company was the primary economic and social hub of the town bogner skikleding 2016. He points out that Flint is the place where the Flint Sit-Down Strike occurred, resulting in the birth of the United Auto Workers. He reveals that his heroes were the Flint natives who had escaped the oppressive life in GM’s factories, including “Flint’s most famous native son”, game show host Bob Eubanks.
Initially, Moore achieves his dream of avoiding factory life after being hired by a magazine in San Francisco, but this venture fails for him and he ultimately travels back to Flint. As he returns (in 1985), GM announces the layoffs of thousands of Flint auto workers, whose jobs will go to cheaper labor in Mexico. GM makes this announcement even though the company is experiencing record profits.
Disguised as a TV journalist, Moore interviews some auto workers in Flint and discovers their strong disgust for GM chairman Roger B. Smith. Moore begins seeking out Smith himself to confront him about the closing of the Flint plants. He tries to visit Smith at GM’s headquarters in Detroit, yet he is blocked by building security as Moore hasn’t made his intentions clear. A company spokesman exchanges contact information with Moore, but ultimately refuses to grant Moore an interview due to fear of negative portrayal. Over the course of the film, Moore attempts to track down Smith at the Grosse Pointe Yacht Club and the Detroit Athletic Club, only to be told either that Smith is not there or to leave by employees and security guards.
From there, Moore begins to explore the emotional impact of the plant closings on his friends. He interviews Ben Hamper, an auto worker who suffered a nervous breakdown on the assembly line and is residing at a mental health facility. From here, to the Beach Boys song “Wouldn’t It Be Nice?”, is seen a montage of the urban decay enveloping Flint, interspersed with news reports about increasing layoffs, residents not being able to move out and rapidly increasing rat infestations. Moore also talks to the residents of the affluent suburb of Grand Blanc, who display classist attitudes about Flint’s hardships; at a roaring twenties-themed party they are hosting, Moore takes note when they hire laid off workers to be human statues.
Moore changes course and turns his camera on the Flint Convention and Visitors Bureau, which promotes a vigorously incompetent tourism policy. The Bureau, in an effort to lure tourists into visiting Flint, permits the construction of a Hyatt Regency Hotel, a festival marketplace called Water Street Pavilion, and AutoWorld, hailed as the world’s largest indoor theme park. All these efforts fail, as the Hyatt files for bankruptcy and is put up for sale, Water Street Pavilion sees most of its stores go out of business, and AutoWorld closes just six months after the grand opening jack wolfskin.
High-profile people are shown coming to Flint to bring hope to the unemployed, some of them interviewed by Moore. Ronald Reagan visits the town and suggests that the unemployed auto workers find work by moving across the country, though the restaurant he visits has its cash register stolen during the event. The mayor pays television evangelist Robert Schuller to preach to the town’s unemployed. Pat Boone and Anita Bryant, who have supplied GM with celebrity endorsements, also come to town; Boone tells Moore that Roger Smith is a “can-do” kind of guy. Moore also interviews Bob Eubanks during a fair near Flint, during which Bob cracks a joke about Jewish women and AIDS.
Moore attends the annual GM’s Shareholders Convention, disguised as a shareholder himself. However, when he gets a turn at the microphone to air his grievances to the board, Smith immediately shuts him out and has the convention adjourned, despite Moore’s attempts to interrupt him. In a close-up of Smith, he is heard joking about his action with a fellow board member before leaving. Meanwhile, Moore meets more residents of Flint, who are reeling from the economic fallout of the layoffs. A former feminist radio host, Janet, joins Amway as a saleswoman to find work. Another resident, Rhonda Britton, sells rabbits for “Pets or Meat”; Britton is featured killing a rabbit by beating it with a lead pipe. Prevalent throughout the film is Sheriff’s Deputy Fred Ross, whose job now demands that he go around town carrying out evictions on families unable to pay their rent.
During all of this, Flint’s crime rate skyrockets, with shootouts and murders becoming all too common. Crime becomes so prevalent that when the ABC News program Nightline tries to do a live story on the plant closings, someone steals the network’s van (along with the cables), abruptly stopping the broadcast. Living in Flint becomes so desperate that Money magazine names the town as the worst place to live in America. The residents react with outrage and stage a rally where issues of the magazine are burned. Ironically, the residents play the song “My Hometown” by Bruce Springsteen during the rally, seemingly unaware it is about a town becoming overcome by crime and poverty.
At the film’s climax, Moore finally confronts Smith at the chairman’s annual 1988 Christmas message in Detroit. Smith is shown expounding about generosity during the holiday season, concurrently as Sheriff Fred Ross evicts more families. After Smith’s speech, Moore hounds Smith, addressing him from a distance. The face-to-face encounter between Michael Moore and Roger B. Smith is shown as this:
Smith: I’ve been to Flint, and I’m sorry for those people, but I don’t know anything about it, but you’d have to…
Moore: Families being evicted from their homes on Christmas Eve.
Smith: Well, I’m… listen, I’m sure General Motors didn’t evict them. You’d have to go talk to their landlords.
Moore: They used to work for General Motors, and now they don’t work there anymore.
Smith: Well, I’m sorry about that.
Moore: Could you come up to Flint with us?
Smith: I cannot come to Flint, I’m sorry.
Dejected by his failure to bring Smith to Flint, Moore proclaims that “as we neared the end of the 20th century”, as the rich got richer and the poor got poorer, and “it was truly the dawn of a new era.” After the credits, the film displays the message “This film cannot be shown within the city of Flint”, followed by “All the movie theatres have closed.”
This film, financed partly by Moore’s mortgaging of his home and partly by the settlement money from a lawsuit he filed against Mother Jones for wrongful termination, was meant to be a personal statement over his anger not just at GM, but also the economic policies and social attitudes of the United States government during the Reagan era, which allows a corporation to remove the largest source of income from an entire town. The film proved to be the most successful documentary in American history at the time in its theatrical run (since surpassed at the box office by Moore’s later documentaries Bowling for Columbine and Fahrenheit 9/11)[citation needed] and enjoyed wide critical acclaim. Despite its success, the film was not nominated for the Best Documentary Feature Academy Award in 1990 bolsos hermes. In response to the documentary, General Motors threatened to pull advertising on any TV show that interviewed Michael Moore.[citation needed] Despite the company’s public opposition to the film, its humorous and buffoon-like portrayal of Roger Smith made it widely popular inside GM; by the time of the film’s release, GM had lost 8% of its market share and was taking on significant financial losses, leading many employees and executives to become disillusioned with Smith’s leadership.
Roger & Me was filmed under the working title A Humorous Look at How General Motors Destroyed Flint, Michigan.
Warner Bros. gave Moore $3 million for distribution license, a very large amount for a first time filmmaker and unprecedented for a documentary. Part of the distribution deal required Warner Bros. to pay rent for two years for the families evicted in the film and give away tens of thousands of tickets to the unemployed workers.
Moore returned to the subject of Roger & Me with a short documentary called Pets or Meat: The Return to Flint (1992), which aired on the PBS show P.O.V. In this film, Moore returns to Flint two years after the release of Roger & Me to see what changes have taken place. Moore revisits Flint and its economic decline again in later films, including The Big One, Bowling for Columbine, Fahrenheit 9/11, and Capitalism: A Love Story.
Film critic Pauline Kael felt the film exaggerated the social impact of GM’s closing of the plant and depicted the actual events of Flint’s troubles out of chronological order. Kael called the film “shallow and facetious, a piece of gonzo demagoguery that made me feel cheap for laughing”. One such criticism is that the eviction at the end of the film occurred on a different day from Smith’s speech, but the two events were intercut for emotional effect. Moore addresses this criticism in the DVD commentary, stating that “there are no dates in the film; we’ll be going back and forth throughout the decade of the ’80s.”
In March 2007, Canadian filmmakers Debbie Melnyk and Rick Caine appeared on MSNBC’s Tucker to talk about their documentary Manufacturing Dissent. They reported to have found that Moore talked with General Motors Chairman Roger Smith at a company shareholders’ meeting, and that this interview was cut from Roger & Me. Moore acknowledged having spoken with Roger Smith at a shareholders’ meeting in 1987, before he commenced filming, but said the encounter concerned a separate topic unrelated to the film. The filmmaker also told the Associated Press that if he had managed to secure an interview with Smith during production, then suppressed the footage, General Motors would have publicized the information to discredit him. “I’m so used to listening to the stuff people say about me, it just becomes entertainment for me at this point,” he remarked. “It’s a fictional character that’s been created with the name of Michael Moore.”
Critic Roger Ebert wrote an article entitled, “Attacks on Roger & Me completely miss the point of film” that defends Moore’s manipulation of his film’s timeline as an artistic and stylistic choice that has less to do with his credibility as a filmmaker and more to do with the flexibility of film as a medium to express a viewpoint using the same methods that satirists have used. Ebert argues that the point of the film is not to present a completely cut and dried presentation of facts, but instead to create a jumping point for interest and dialogue through use of humor and irony.
Critic Billy Stevenson described the film as Moore’s “most astonishing”, arguing that it represents an effort to conflate film-making and labor, and that “it’s this fusion of film-making and work that allows Moore to fully convey the desecration of Flint without ever transforming it into a sublime or melancholy poverty-spectacle, thereby distancing himself from the retouristing of the town-as-simulacrum that occupies the last and most intriguing part of the film.” As of August 2014, Roger & Me has a Rotten Tomatoes rating of 100%, with all 27 cited professional reviews being positive.
The film received the 1989 Best Documentary award from the National Board of Review.

Malais (peuple)

Les princes des sultanats de Deli, Langkat et Serdang à l’époque des Indes néerlandaises
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On appelle Malais (orang Melayu) les populations de la côte est de l’île indonésienne de Sumatra, des îles Riau, également indonésiennes, du littoral de l’île de Bornéo, de la péninsule Malaise, de Singapour et du sud de la Thaïlande (provinces de Yala, Pattani 2016 Collection Sandro Femme, Narathiwat et Songkhla) qui parlent des langues appartenant au groupe linguistique dit “malais”.
Toutefois, le fait de parler une langue appartenant à ce groupe linguistique ne suffit pas à caractériser un Malais. C’est évident pour les locuteurs de langues classées “Trade Malay” (“malais du commerce”). Mais des populations voisines des Malais, comme les Minangkabau de l’ouest de Sumatra ou les Musi de la région de Palembang dans le sud de Sumatra, ne se considèrent pas comme “Malais” qui est en l’occurrence un terme identitaire.
Il faut en outre insister sur le fait que les Malais n’habitent pas uniquement la péninsule Malaise, qui n’est d’ailleurs pas le territoire d’origine des Malais. Malayu désignait d’ailleurs un royaume de l’est de Sumatra, dont le nom est attesté par des textes chinois dès le VIIe siècle de notre ère 2016 soccer jerseys en ligne.
Quant au nom de “Malaisie” (Tanah Melayu), d’un point de vue malaisien, il désigne seulement la partie malaisienne de la péninsule de Malacca. Mais en français adidas soccer jerseys 2016 outlet, “Malaisie” désigne aussi la fédération (Persekutuan Malaysia), qui outre la péninsule, comprend les Etats de Sabah et Sarawak dans le nord de Bornéo (le nom local de la fédération est “Malaysia”). Le nom “Malaisie” a pour origine l’expression Malaisie britannique (British Malaya en anglais), créée au XIXe siècle pour désigner les sultanats de la péninsule sous protectorat britannique 2016 Collection Sandro Femme, et pour les distinguer des sultanats malais de Sumatra et du sud de Bornéo, sous souveraineté néerlandaise.

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Pyramid (image processing)

Pyramid, or pyramid representation, is a type of multi-scale signal representation developed by the computer vision, image processing and signal processing communities, in which a signal or an image is subject to repeated smoothing and subsampling. Pyramid representation is a predecessor to scale-space representation and multiresolution analysis.

There are two main types of pyramids: lowpass and bandpass.
A lowpass pyramid is made by smoothing the image with an appropriate smoothing filter and then subsampling the smoothed image, usually by a factor of 2 along each coordinate direction. The resulting image is then subjected to the same procedure, and the cycle is repeated multiple times. Each cycle of this process results in a smaller image with increased smoothing, but with decreased spatial sampling density (that is, decreased image resolution). If illustrated graphically, the entire multi-scale representation will look like a pyramid, with the original image on the bottom and each cycle’s resulting smaller image stacked one atop the other.
A bandpass pyramid is made by forming the difference between images at adjacent levels in the pyramid and performing some kind of image interpolation between adjacent levels of resolution, to enable computation of pixelwise differences.
A variety of different smoothing kernels have been proposed for generating pyramids. Among the suggestions that have been given, the binomial kernels arising from the binomial coefficients stand out as a particularly useful and theoretically well-founded class. Thus, given a two-dimensional image, we may apply the (normalized) binomial filter (1/4, 1/2, 1/4) typically twice or more along each spatial dimension and then subsample the image by a factor of two. This operation may then proceed as many times as desired, leading to a compact and efficient multi-scale representation. If motivated by specific requirements, intermediate scale levels may also be generated where the subsampling stage is sometimes left out, leading to an oversampled or hybrid pyramid. With the increasing computational efficiency of CPUs available today victoria beckham dresses, it is in some situations also feasible to use wider support Gaussian filters as smoothing kernels in the pyramid generation steps.
In a Gaussian pyramid, subsequent images are weighted down using a Gaussian average (Gaussian blur) and scaled down. Each pixel containing a local average that corresponds to a pixel neighborhood on a lower level of the pyramid. This technique is used especially in texture synthesis.
A Laplacian pyramid is very similar to a Gaussian pyramid but saves the difference image of the blurred versions between each levels. Only the smallest level is not a difference image giuseppe zanotti sneakers men, to enable reconstruction of the high resolution image using the difference images on higher levels dior online. This technique can be used in image compression.
A steerable pyramid is an implementation of a multi-scale, multi-orientation band-pass filter bank used for applications including image compression, texture synthesis, and object recognition. It can be thought of as an orientation selective version of a Laplacian pyramid, in which a bank of steerable filters are used at each level of the pyramid instead of a single Laplacian of Gaussian filter.
In the early days of computer vision, pyramids were used as the main type of multi-scale representation for computing multi-scale image features from real-world image data. More recent techniques include scale-space representation, which has been popular among some researchers due to its theoretical foundation, the ability to decouple the subsampling stage from the multi-scale representation, the more powerful tools for theoretical analysis as well as the ability to compute a representation at any desired scale gucci bags sale, thus avoiding the algorithmic problems of relating image representations at different resolution. Nevertheless, pyramids are still frequently used for expressing computationally efficient approximations to scale-space representation.
Laplacian image pyramids based on the bilateral filter provide a good framework for image detail enhancement and manipulation. The difference images between each layer are modified to exaggerate or reduce details at different scales in an image.
Some image compression file formats use the Adam7 algorithm or some other interlacing technique. These can be seen as a kind of image pyramid. Because those file format store the “large-scale” features first, and fine-grain details later in the file, a particular viewer displaying a small “thumbnail” or on a small screen can quickly download just enough of the image to display it in the available pixels—so one file can support many viewer resolutions, rather than having to store or generate a different file for each resolution.

Nelson, Oklahoma

Nelson is an unincorporated community in northwestern Choctaw County, Oklahoma. It is six miles north of Soper, Oklahoma.
Spencer Academy, a Choctaw Nation school, was moved here from Spencerville giuseppe zanotti, Oklahoma. A United States Post Office was established at Nelson, Indian Territory on March 10 canada goose online, 1881 and operated until November 30, 1954. Until September 15, 1881, the official name of this post office was Nelsons. Nelson is named for Cole E. Nelson, prominent Choctaw Indian and National Attorney of the Choctaw Nation.
Until the advent of Oklahoma’s statehood Nelson was located in Kiamitia County (Kiamichi County), Choctaw Nation.
Nelson’s livelihood as a commercial and population center was threatened after the St. Louis and San Francisco Railway built its tracks east of Nelson, passing instead through the communities of Antlers, Hamden, Speer and Hugo ted baker deutschland. Although it retained a lively community for decades following the railroad’s construction in the 1880s, the towns along the railroad sapped it of potential commercial success.
Nelson continues to be home to several families, and as such remains the area’s oldest settlement

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Cooper v. Pate

Cooper v. Pate, 378 U.S. 546 (1964), was a U 2016 dior schoenen.S. Supreme Court case in which the court ruled for the first time that state prison inmates have the standing to sue in federal court to address their grievances under the Civil Rights Act of 1871. This case followed Jones v 2016 chanel tassen. Cunningham (1963) allowing prison inmates to employ a writ of habeas corpus to challenge the legality of their sentencing and the conditions of their imprisonment.

The petitioner, an inmate at the Illinois State Prison, brought a writ of certiorari alleging that solely because he was a Black Muslim he was denied permission to buy religious publications and also denied other privileges accorded other prisoners. The District Court had granted the respondent’s motion to dismiss for failure to state a claim for which relief could be granted prada tassen 2016. The Court of Appeals affirmed.
The Supreme Court reversed the judgment, stating the lower courts were in error to dismiss the stated cause of action as the petitioner is entitled to have his case heard on its merits 2016 chanel schoenen.
This case made clear that prison authorities must do whatever is within their ability to treat individuals of every religious group equally, unless they can demonstrate good reasons to do otherwise.

Fairbanks Township, Michigan

Fairbanks Township is a civil township of Delta County in the U.S. state of Michigan. As of the 2000 census, the township population was 321.

According to the United States Census Bureau, the township has a total area of 299.2 square miles (775 km2), of which 47.2 square miles (122 km2) is land and 252.0 square miles (653 km2) (84.23%) is water 2016 billig Adidas fotboll jacka utlopp.
As of the census of 2000, there were 321 people, 143 households, and 93 families residing in the township. The population density was 6.8 per square mile (2.6/km²). There were 267 housing units at an average density of 5.7 per square mile (2.2/km²). The racial makeup of the township was 91.59% White, 4.98% Native American, 0.31% Asian, and 3.12% from two or more races.
There were 143 households out of which 19.6% had children under the age of 18 living with them, 56.6% were married couples living together, 7.0% had a female householder with no husband present 2016 Puma fotbollsskor på nätet, and 34 2016 lågpris Nike fotbollsskor.3% were non-families. 30.1% of all households were made up of individuals and 14.0% had someone living alone who was 65 years of age or older. The average household size was 2.24 and the average family size was 2.76.
In the township the population was spread out with 15.6% under the age of 18, 6.9% from 18 to 24, 24.9% from 25 to 44, 31 2016 billig Adidas fotboll jacka utlopp.2% from 45 to 64, and 21.5% who were 65 years of age or older. The median age was 47 years. For every 100 females there were 100.6 males. For every 100 females age 18 and over, there were 100.7 males.
The median income for a household in the township was $24,643, and the median income for a family was $32,500. Males had a median income of $28,214 versus $25,417 for females. The per capita income for the township was $15,327. About 14.0% of families and 12.3% of the population were below the poverty line, including 12.0% of those under age 18 and 12.3% of those age 65 or over.

Egosoft

Egosoft — немецкая компания по разработке компьютерных видеоигр, основанная в 1988 году, базирующаяся в городе Вюрзелен bogner москва, Германия. Изначально делали игры под платформу Amiga, а позже перешли на игры для персональных компьютеров.
Egosoft известна благодаря собственной серии космических симуляторов во Вселенной X, особенностью которых является открытая вселенная-«песочница» bogner одежда, развитая экономическая модель и длительная сюжетная линия. Первая игра серии вышла в 1999 году, а по состоянию на январь 2013 года насчитывает 6 компьютерных игр: два сиквела и два полномасштабных дополнения. Последнее дополнение X³: Albion Prelude вышло в 2011 году. Тогда же Egosoft анонсировал перезапуск серии новой игрой X Rebirth, которая должна выйти эксклюзивно на PC 15 ноября 2013 года.

Версии под Linux и MacOS разрабатывались силами сторонних компаний: Linux Game Publishing и Virtual Programming. Ltd.
В 2000 году Egosoft обнародовала планы по созданию онлайн-игры во Вселенной X под кодовым названием Online Universe (или X Online). Этот проект был призвал «стать следующим шагом в эволюции Вселенной Х от Egosoft». Однако с тех пор компания выпустила несколько игр в серии X, но о прогрессе в разработке онлайн-проекта известий не поступало. В 2003 году Egosoft сообщила, что они работают над проектом «X2OL», который директор Egosoft назвал «нашей долгосрочной целью». Несмотря на то, что никакой официальной информации об онлайн-игре нет, ходили слухи, что поддержка онлайн могла появиться в играх X² и X³.
В конце 2009 года представитель Egosoft рассказал, что дополнение Terran Conflict станет последней части в сюжетной линии, начатой в X: Beyond The Frontier в 1999 году. Многие восприняли это как объявлении об окончании франшизы, однако в марте 2011 года на форуме Вселенной Х разработчики написали, что на выставке FedCon, которая должна была начаться 28 апреля 2011 года в Дюссельдорфе, компания Egosoft анонсирует новый проект во Вселенной Х, перезапускающий серию, назвав его TNBT («The Next Big Thing», «Следующая Большая Вещь»). Однако уже 20 апреля был выпущен трейлер дешевым Adidas футбола, официально анонсирующий новую компьютерную игру X Rebirth на выходе Nike футбол оборудование, которую должны были выпустить уже в 4 квартале 2011 года. Сюжет X Rebirth развивается в той же вселенной, в которой произошла глобальная катастрофа, приведшая к отключению звездных врат. Таким образом, сюжет новой игры отделен от предыдущих игр и открывает новую главу в истории Вселенной X. 15 декабря 2011 вышло дополнение X³: Albion Prelude к X³: Terran Conflict, в котором появились новые корабли, сектора и сюжетная линия, началось строительство магистралей, которые должны появиться в X Rebirth.